Spanning two decades, the collaborative ENCODE project aims to identify all the functional elements within human and mouse genomes. To best serve the scientific community, the comprehensive ENCODE ...

Large-scale annotation efforts over the past two decades have identified regulatory regions and networks through functional genomics and evolutionary analyses. The challenge now will be to incorporate ...

Typically, the information encoded in DNA allows organisms to develop, function, and pass traits across generations. Yet DNA ...

Gene regulation is the process by which cells control the expression of their genes, determining when, where, and to what extent each gene is expressed. It is a fundamental mechanism that allows cells ...