The production of biotherapeutics involves many unit operations, and it is common practice to store in-process material as dictated by the manufacturing setup and scheduling of unit operations. The ...

Recombinant proteins can be produced using many types of cells including, yeast, bacteria, insect and mammalian cells. What advantages are there to producing recombinant proteins using mammalian cells ...

Monoclonal antibody expression systems typically utilise a signal peptide to ensure secretion of the antibody into the cell culture medium. Although this reduces the complexity of purification and ...

Optimizing the clarification of cell culture or fermentation broth is generally seen as a limited contributor to critical quality attributes (CQA). Researchers at Merck, however, say it’s time to ...

Antibodies are essential proteins produced by the immune system that recognize and bind to specific targets, known as antigens. Their high specificity and affinity make antibodies invaluable tools in ...

A novel method to improve the high-yield, high-purity, high-activity purification of complex proteins by 10- to 500-fold has been developed by scientists. The new method offers crucial advantages to ...

Recombinant baculoviruses (rBVs) are widely used as vectors for the production of recombinant proteins in insect cells. More recently, these viral vectors have been gaining increasing attention due to ...

Monoclonal antibodies (mAbs) are an important class of therapeutics. In recent years, however, increased attention has been devoted to the development of next-generation biologic therapeutics and ...

WESTBOROUGH, MASSACHUSETTS, June 24, 2020 — Pall Laboratory, a global leader in proven filtration, separation and sample preparation solutions, has introduced two AcroPrep™ 24-well filter plates. The ...

A novel method to improve the high-yield, high-purity, high-activity purification of complex proteins by 10- to 500-fold has been developed at the University of Alabama at Birmingham. "This new method ...